Functional polymorphisms in the paternally expressed XLαs and its cofactor ALEX decrease their mutual interaction and enhance receptor-mediated cAMP formation resulting in platelet Gs hyperfunction

Freson, Kathleen; Thys, Chantal; Van kerckhoven, Soetkin; Wittevrongel, Marie-Christin; Vermylen, Jozef; Hoylaerts, Marc; Van Geet, Christel

Journal of Thrombosis and Haemostasis

Functional polymorphisms in the paternally expressed XLαs and its cofactor ALEX decrease their mutual interaction and enhance receptor-mediated cAMP formation resulting in platelet Gs hyperfunction

Author:

Freson, Kathleen

Thys, Chantal ; Van kerckhoven, Soetkin ; Wittevrongel, Marie-Christin ; Vermylen, Jozef ; Hoylaerts, Marc ; Van Geet, Christel

Keywords:

1102 Cardiorespiratory Medicine and Haematology, 1103 Clinical Sciences, Cardiovascular System & Hematology, 3201 Cardiovascular medicine and haematology, 3202 Clinical sciences

Journal of Thrombosis and Haemostasis Functional polymorphisms in the paternally expressed XLαs and its cofactor ALEX decrease their mutual interaction and enhance receptor-mediated cAMP formation resulting in platelet Gs hyperfunction

Author:

Keywords:

Journal of Thrombosis and Haemostasis

Functional polymorphisms in the paternally expressed XLαs and its cofactor ALEX decrease their mutual interaction and enhance receptor-mediated cAMP formation resulting in platelet Gs hyperfunction