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Title: Underwater Nd:YAG laser coagulation of blood vessels in a rat model
Authors: Evrard, V A ×
Deprest, Jan
Van Ballaer, P
Lerut, Antoon
Vandenberghe, Katleen
Brosens, I A #
Issue Date: Nov-1996
Series Title: Fetal diagnosis and therapy vol:11 issue:6 pages:422-6
Abstract: Endoscopic coagulation of placental and umbilical cord vessels has been suggested as a treatment for selected cases of twin-twin transfusion syndrome and of acardiac twin. The feasibility, safety and hemostatic effect of neodymium:yttrium-aluminium-garnet (Nd:YAG) laser in an underwater environment were experimentally studied in an in vivo model, mimicking the in utero situation and fetoplacental vessels. In 10 male Wistar rats, immersed in normal saline at 38 degrees C, femoral vessels, carotid artery, abdominal aorta and vena cava were coagulated under endoscopic control. A 100-Watt Nd:YAG laser was used in continuous mode with a 600-micron fiber. Outcome measurements were vascular diameter, total energy (joules) used to obtain visual coagulation and subsequent vascular obliteration. Overall failure rate was 32% and perforation of the vessel occurred in 7.7% of cases.
ISSN: 1015-3837
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Cardiology
Foetal Medicine Section (-)
Thoracic Surgery
× corresponding author
# (joint) last author

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