Title: The diagnostic problem of endometrial stromal sarcoma: report on six cases
Authors: Amant, Frédéric ×
Moerman, Philippe
Cadron, Isabelle
Neven, Patrick
Berteloot, Patrick
Vergote, Ignace #
Issue Date: Jul-2003
Publisher: Academic Press
Series Title: Gynecologic Oncology vol:90 issue:1 pages:37-43
Abstract: OBJECTIVE: The objective was to look for the incidence and clinicopathologic findings of women in whom the diagnosis of endometrial stromal sarcoma was initially missed. METHODS: We carried out a retrospective analysis of cases treated at our institution from 1990 to 2002. RESULTS: In 6/15 (40%) women suffering from endometrial stromal sarcoma, the diagnosis initially was missed. The first diagnosis was uterine leiomyoma (n = 2), myxoid leiomyoma (n = 2), cellular leiomyoma (n = 1), or lymphatic disorder (n = 1). The final diagnosis was only made after consultation of a pathologist with a special interest in gynecological oncology. The mean age of this group was only 34 years (range, 18-53). A mean delay in diagnosis of 143 months (range, 24-408) resulted in stage 4 disease in 5/6 women. After a mean follow-up of 16 years (range, 5-43), 4/6 are without macroscopic evidence of disease, 1/6 with evidence of disease, and 1/6 died of disease. CONCLUSION: Especially in younger women, the diagnosis of endometrial stromal sarcoma can be problematic.
ISSN: 0090-8258
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Gynaecological Oncology
Translational Cell & Tissue Research
Section Woman - Miscellaneous (-)
× corresponding author
# (joint) last author

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