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Title: Add-on therapy of fenfluramine in intractable self-induced epilepsy
Authors: Boel, Marc ×
Casaer, Paul #
Issue Date: Aug-1996
Series Title: Neuropediatrics vol:27 issue:4 pages:171-3
Abstract: Eleven institutionalized children (7 girls, 4 boys) with refractory epilepsy received fenfluramine as add-on therapy. Besides therapy resistance, the patients manifested self-induction of seizures. Eight patients were photosensitive and/or pattern sensitive. All antiepileptic drugs of doubtful efficacy were withdrawn. During withdrawal, patients did neither improve nor show an increase in seizure frequency. Fenfluramine was then added and administered once to three times daily at dosages between 0.5 and 1 mg/ Side effects were mild and transient. Of the 11 patients, 7 became seizure-free and in 4 patients a more than 75% decrease of all seizures was obtained.
ISSN: 0174-304X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Section Child - Miscellaneous (-)
Faculty of Medicine - miscellaneous
× corresponding author
# (joint) last author

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