Title: Structure-activity relationship of short-chain sphingoid bases as inhibitors of sphingosine kinase
Authors: De Jonghe, Steven ×
Van Overmeire, I
Poulton, S
Hendrix, Christel
Busson, Roger
Van Calenbergh, Serge
De Keukeleire, Denis
Spiegel, S
Herdewijn, Piet #
Issue Date: 1999
Series Title: Bioorganic & medicinal chemistry letters vol:9 issue:21 pages:3175-3180
Abstract: Short-chain sphinganine analogues 8, 9, 18, and 19, as well as 3-fluoro-sphingosine analogues 25 and 26 were synthesized. Their potential as sphingosine kinase inhibitors was investigated, in combination with previously synthesized sphingosine and fluorinated sphinganine analogues.
ISSN: 0960-894X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

Files in This Item:
File Description Status SizeFormat
3097.pdf Published 331KbAdobe PDFView/Open Request a copy

These files are only available to some KU Leuven Association staff members


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science