Title: A short path synthesis of [C-13/N-15] multilabeled pyrimidine nucleosides starting from glucopyranose nucleosides
Authors: Lagoja, Irene
Pochet, Sylvie
Boudou, Valerie
Little, Roy
Lescrinier, Eveline
Rozenski, Jef
Herdewijn, Piet # ×
Issue Date: Mar-2003
Publisher: Amer chemical soc
Series Title: Journal of Organic Chemistry vol:68 issue:5 pages:1867-71
Abstract: The synthesis of fully [13C/15N] labeled pyrimidine nucleosides has been achieved from 13C-glucose and labeled nucleobases. The reaction scheme leads directly to the protected nucleosides without the need for the inversion of configuration of C-3 of 13C-glucose. This was achieved by an oxitative ring-opening reaction removing the carbon with the wrong configuration.
ISSN: 0022-3263
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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