Title: Dietary influences on 8-MOP plasma levels in PUVA patients with psoriasis
Authors: Roelandts, Rik ×
Van Boven, Maurits
Deheyn, T
Vander Stichele, G
Degreef, Hugo
Daenens, Paul #
Issue Date: 1981
Series Title: British Journal of Dermatology vol:105 issue:5 pages:569-72
Abstract: To study the effect of diet on 8-MOP plasma levels, these levels were measured three times in twenty PUVA patients with psoriasis; while fasting, after a low-fat breakfast, and after a fat-rich breakfast. No significant differences were found between the maximal 8-MOP plasma levels in the fasting condition and the levels after the low-fat breakfast, both peaking 2 h after ingestion. After the fat-rich breakfast, however, the 8-MOP plasma levels were not only significantly lower at 2 h but also peaked later, reaching their maximum at 3-4 h after intake. The drug should therefore be given in a dietetically standardized way. This raises the question whether some cases of therapy resistance can be dietetically influenced.
ISSN: 0007-0963
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Dermatology
Toxicology and Pharmacology
Laboratory of Dermatoimmunology (+)
× corresponding author
# (joint) last author

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