Title: Facilitated column selection in pharmaceutical analyses using a simple column classification system
Authors: Visky, Dóra ×
Haghedooren, Erik
Dehouck, Pieter
Kovács, Zsuzsanna
Kóczián, Kristof
Noszál, Béla
Hoogmartens, Jos
Adams, Erwin #
Issue Date: Jan-2006
Series Title: Journal of Chromatography A vol:1101 issue:1-2 pages:103-114
Abstract: In this paper, the performance of a previously developed classification system applied to pharmaceutical chromatographic analyses, is investigated. The separation of seven different drug substances from their respective impurities was studied. The chromatographic procedure for acetylsalicylic acid, clindamycin hydrochloride, buflomedil hydrochloride, chloramphenicol sodium succinate, nimesulide and phenoxymethylpenicillin was performed according to the corresponding European Pharmacopoeia (Ph. Eur.) monograph. The separation of dihydrostreptomycin sulphate was performed according to the literature. It is shown that the column ranking system is a helpful tool in the selection of a suitable column in these analyses.
ISSN: 0021-9673
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Pharmaceutical Analysis
× corresponding author
# (joint) last author

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