Title: Diagnostic value of 99Tcm-d,l-HMPAO-labelled leukocyte scintigraphy in the detection of vascular graft infections
Authors: Krznaric, E ×
Nevelsteen, André
van Hoe, L
De Roo, Michel
Schiepers, C
Verbruggen, Alfons
Mortelmans, Luc #
Issue Date: Dec-1994
Publisher: Chapman hall ltd
Series Title: Nuclear medicine communications vol:15 issue:12 pages:953-60
Abstract: Prosthetic vascular graft infection is a relatively uncommon complication of peripheral vascular surgery. We retrospectively analysed technetium-99m-d,l-hexamethylpropylene amine oxime (99Tcm-d,l-HMPAO) labelled leukocyte scans of 21 patients with a suspected vascular graft infection. Operative findings, bacteriological cultures, radiological findings or clinical follow-up were used to confirm the diagnosis. We found eight true-positive and six true-negative cases. There were no false-positive scintigraphic diagnoses. The false-negative rate was 33% (n = 7). Our results show a sensitivity of 53%, a specificity of 100% and an accuracy of 66%. The conclusion is that a negative 99Tcm-d,l-HMPAO-labelled leukocyte scan is of limited value in ruling out a vascular graft infection. A combination of computed tomography (CT-scan) and a 99Tcm-d,l-HMPAO-labelled leukocyte scan is probably the most efficient way of diagnosing a vascular graft infection.
ISSN: 0143-3636
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Vascular Surgery
Radiopharmaceutical Research
Nuclear Medicine & Molecular Imaging
× corresponding author
# (joint) last author

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