Title: Minimal number of chromatographic test parameters for the characterisation of reversed-phase liquid chromatographic stationary phases
Authors: Iványi, Timea ×
Vander Heyden, Yvan
Visky, Dóra
Baten, Peggy
De Beer, Jacques
Lázár, István
Massart, D L
Roets, Eugene
Hoogmartens, Jos #
Issue Date: Apr-2002
Series Title: Journal of Chromatography A vol:954 issue:1-2 pages:99-114
Abstract: This paper focuses on the classification or differentiation of RP-HPLC columns based on measured chromatographic properties. A chemometric study has been conducted on a published data set consisting of 85 RP-HPLC columns and on a data set consisting of 47 self-tested columns. Principal component analysis enables determination of the number of parameters necessary for a rational differentiation. The results show that reducing the number of parameters for such differentiation still allows classification of the columns just as a higher number did. It is shown that three test parameters produce a classification similar to that obtained with five parameters.
ISSN: 0021-9673
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Pharmaceutical Analysis
× corresponding author
# (joint) last author

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