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Title: Synthesis and antiviral activity of a series of new cyclohexenyl nucleosides
Authors: Gu, Ping
Morral, J
Wang, J
Rozenski, Jef
Busson, Roger
Van Aerschot, Arthur
De Clercq, Erik
Herdewijn, Piet # ×
Issue Date: Jan-2003
Publisher: Blackwell Scientific Publications
Series Title: Antiviral Chemistry & Chemotherapy vol:14 issue:1 pages:31-37
Abstract: A series of new cyclohexenyl nucleosides is synthesized by coupling the heterocyclic bases with a protected cyclohexenyl precursor under Mitsunobu conditions. The compounds were evaluated for their antiviral and cytostatic activity. Pronounced activity against herpes simplex virus type 1 and type 2 was observed for the 2,6-diaminopurine analogue.
ISSN: 0956-3202
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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