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Title: Synthesis of pyrazino[1,2-a]benzimidazol-1(2H)ones via a microwave assisted Buchwald-Hartwig type reaction
Authors: Alen, Jo
Robeyns, Koen
De Borggraeve, Wim ×
Van Meervelt, Luc
Compernolle, Frans #
Issue Date: Aug-2008
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron vol:64 issue:35 pages:8128-8133
Abstract: A convenient synthesis of substituted pyrazino[1,2-a]benzimidazol-1(2H)ones starting from 3,5-dichloropyrazinones has been accomplished. Various 3-anilino-pyrazinones were easily converted to the desired tricyclic structures by applying a microwave assisted Buchwald-Hartwig type cyclization. (C) 2008 Elsevier Ltd. All rights reserved.
URI: 
ISSN: 0040-4020
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
Biochemistry, Molecular and Structural Biology Section
Chemistry - miscellaneous
× corresponding author
# (joint) last author

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