Journal of clinical neurophysiology vol:25 issue:4 pages:202-209
Purpose: Evaluate the delayed effects of repetitive sensory stimulation with passive wrist movement on corticospinal excitability of the forearm and hand musculature.
Methods: Motor evoked potential (MEPs) responses to single and double pulse transcranial magnetic stimulation (TMS) were recorded from the flexor carpi radialis (FCR), extensor carpi radialis (ECR) and the first dorsal interosseus (FDI) muscles of the right limb. Data were collected before and after a 1 hour session of passive wrist movement (intervention group, n=11) or after a same period of rest (control group, n=9). MEP size and area were analyzed to evaluate corticospinal excitability as well as short interval intracortical inhibition (SICI) and facilitation (ICF).
Results: Training with passive movement resulted in a prolonged increase in corticospinal excitability in the FCR and ECR (until at least 1 hour post intervention), but did not evoke significant changes in the levels of SICI and ICF. No such effects were noted in the control group or FDI muscle.
Conclusion: Prolonged proprioceptive stimulation with passive wrist movement induces a delayed increase in corticospinal excitability of the forearm muscles. Accordingly, this intervention may promote motor cortical reorganization in the targeted muscles.
Significance: Results show induced effects from passive movement training that may prove useful for neurorehabilitation therapies.