Title: Ocular pulse amplitude in normal tension and primary open angle glaucoma
Authors: Stalmans, Ingeborg ×
Harris, Alon
Vanbellinghen, Veerle
Zeyen, Thierry
Siesky, Brent #
Issue Date: Aug-2008
Publisher: Lippincott williams & wilkins
Series Title: Journal of glaucoma vol:17 issue:5 pages:403-407
Abstract: PURPOSE: (1) To investigate the relationship of ocular pulse amplitude (OPA) with intraocular pressure (IOP) and corneal thickness. (2) To evaluate OPA in patients with primary open angle and normal tension glaucoma (NTG). METHODS: Patients with NTG (n=28), primary open angle glaucoma (POAG) (n=19), and age-matched healthy controls (n=22) underwent 2 consecutive Goldmann and dynamic contour tonometry measurements within 1 month. Central corneal thickness was also measured. A regression model was applied to compare OPA between the diagnostic groups. RESULTS: OPA increased with rising IOP (slope 0.026/0.033 and P=0.002/<0.0001 for Goldmann/Dynamic tonometry), whereas corneal thickness did not influence pulse amplitude measurements (slope-0.0017/-0.0013 and P=0.11/0.21 after correction for Goldmann/Dynamic tonometry). In a multivariate model correcting for IOP and corneal thickness, OPA was reduced in patients with NTG (P=0.014/0.017 corrected for Goldmann/Dynamic tonometry) or POAG (P=0.015/0.014). CONCLUSIONS: OPA is reduced in normal tension and POAG patients compared with healthy controls. OPA is influenced by IOP, but not by corneal thickness.
ISSN: 1057-0829
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Research Group Ophthalmology
× corresponding author
# (joint) last author

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