Title: Mediators of the association between depression and role functioning
Authors: Buist-Bouwman, M A ×
Ormel, J
de Graaf, R
de Jonge, P
van Sonderen, E
Alonso, J
Bruffaerts, Ronny
Vollebergh, W A M #
Issue Date: Dec-2008
Publisher: Munksgaard
Series Title: Acta Psychiatrica Scandinavica vol:118 issue:6 pages:451-458
Abstract: Mediators of the association between depression and role functioning.Objective: While the adverse effect of Major Depressive Episode on role functioning is well established, the exact pathways remain unclear. Method: Data from The European Study of the Epidemiology of Mental Disorders, a cross-sectional survey including 21 425 adults from six European countries, were used to assess 12-month depression (Composite International Diagnostic Interview), activity limitations and role functioning in the past 30 days (Disability Assessment Schedule). An a priori model based on the World Health Organization's International Classification of Functioning, Disability and Health was designed and a structural equation model for categorical and ordinal data was used (MPlus) to estimate the extent to which six limitations mediated the association between depression and role functioning. Results: The unadjusted association between depression and role functioning was strong (0.43; SE = 0.04). In the best-fitting model, only concentration and attention problems and embarrassment mediated a significant amount of association (direct effect dropped to 0.17; SE = 0.10, which was no longer significant). Conclusions: Targeting cognition and embarrassment in treatment could help reduce depression-associated role disfunctioning.
ISSN: 0001-690X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Research Group Psychiatry
× corresponding author
# (joint) last author

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