Title: Sarcoma arising from interdigitating reticulum cells: reports of a case, studied with light and electron microscopy, and enzyme- and immunohistochemistry
Authors: van den Oord, Joost ×
De Wolf-Peeters, Christiane
De Vos, Rita
Thomas, José
Desmet, Valeer #
Issue Date: May-1986
Publisher: Blackwell Scientific Publications
Series Title: Histopathology vol:20 pages:509-523
Abstract: The morphological, enzyme- and immunohistochemical features of a sarcoma arising from interdigitating reticulum cells (IDRC) are presented. These cells are normal constituents of the T-dependent region of lymphoid organs, and their function is largely unresolved. The immunohistochemical findings in the present case indicate that neoplastic IDRC are morphologically and phenotypically similar to normal IDRC in lymphoid organs. Functionally however, neoplastic IDRC more closely resemble IDRC in the fetal lymph node and in the thymus, where they are thought to play a role in the final differentiation of immature thymocytes into mature peripheral T-lymphocytes.
ISSN: 0309-0167
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Oncology - miscellaneous
Translational Cell & Tissue Research
× corresponding author
# (joint) last author

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