Title: Oligonucleotides with cyclohexene-nucleoside building blocks: crystallization and preliminary X-ray studies of a left-handed sequence GTGTACAC
Authors: Robeyns, Koen ×
Herdewijn, Piet
Van Meervelt, Luc #
Issue Date: 2005
Series Title: Acta crystallographica. Section F, Structural biology and crystallization communications vol:61 issue:Pt 6 pages:585-586
Abstract: Cyclohexene nucleic acids contain a cyclohexene ring instead of the normal beta-D-2'-deoxyribose. The cyclohexene oligonucleotide GTGTACAC was synthesized using phosphoramidite chemistry and standard protecting groups. Crystals of GTGTACAC were obtained at 289 K by the hanging-drop vapour-diffusion technique. The crystals diffract to 1.7 A resolution and belong to the trigonal space group R3, with unit-cell parameters a = 41.434, c = 66.735 A.
ISSN: 1744-3091
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Biochemistry, Molecular and Structural Biology Section
Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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