Title: The association between cognition and functional outcome in first-episode patients with schizophrenia: mystery resolved?
Authors: van Winkel, R ×
Myin-Germeys, Inez
De Hert, Marc
Delespaul, P
Peuskens, Joseph
van Os, J #
Issue Date: Aug-2007
Series Title: Acta psychiatrica Scandinavica vol:116 issue:2 pages:119-124
Abstract: OBJECTIVE: The presence of a prospective association between cognition and functional outcome in first episode patients with schizophrenia is much debated. METHOD: Associations between Intelligence Quotient (IQ) measures and functional outcome were assessed at the first hospitalization and after 10 years follow-up. RESULTS: Functional outcome was associated with estimated premorbid IQ and IQ at 10-year follow-up, but not with IQ assessed at first hospitalization. CONCLUSION: The presence of a prospective as well as a cross-sectional relationship of the global cognitive measure IQ with 10-year functional outcome could be established. However, assessing associations between cognitive measures assessed at first hospitalization and subsequent functional outcome, can give inconclusive results due to non-uniform intellectual deterioration from premorbid level in the period preceding the first hospitalization.
ISSN: 0001-690X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:University Centre Sint Jozef (-)
Research Group Psychiatry
× corresponding author
# (joint) last author

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