Title: Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose
Authors: Rabijns, Anja ×
Barre, Annick
Van Damme, Els J M
Peumans, Willy J
De Ranter, Camiel
Rougé, Pierre #
Issue Date: Jul-2005
Series Title: The FEBS journal vol:272 issue:14 pages:3725-32
Abstract: The structures of MornigaM and the MornigaM-mannose complex have been determined at 1.8 A and 2.0 A resolution, respectively. Both structures adopt the typical beta-prism motif found in other jacalin-related lectins and their tetrameric assembly closely resembles that of jacalin. The carbohydrate-binding cavity of MornigaM readily binds mannose. No major structural rearrangements can be observed in MornigaM upon binding of mannose. These results allow corroboration of the structure-function relationships within the small group of Moraceae lectins.
ISSN: 1742-464X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Biocrystallography
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× corresponding author
# (joint) last author

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