Nucleic Acids Symposium Series issue:52 pages:263-4
Joint Symposium of the 18th International Round Table on Nucleosides, Nucleotides and Nucleic Acids and the 35th International Symposium on Nucleic Acids Chemistry location:Kyoto, Japan date:8-12 September 2008
A dideoxythymidine analog, viz. 3'-N, N-dimethyl-2'-3'-dideoxythymidine (3) and its 5'-O-carboxyl ester prodrug derivatives (4-6) have been synthesized as probable antiviral agents. All these compounds have shown low to moderate level of antiviral activities against HIV, HSV 1 & 2, reovirus and many others.