Title: Thymidine analogs as potential antiviral agents
Authors: Yadav, Dipti
Rai, Diwakar
Balzarini, Jan
De Clercq, Erik
Singh, Ramendra K #
Issue Date: 8-Sep-2008
Publisher: Information Retrieval Ltd.
Host Document: Nucleic Acids Symposium Series issue:52 pages:263-4
Conference: Joint Symposium of the 18th International Round Table on Nucleosides, Nucleotides and Nucleic Acids and the 35th International Symposium on Nucleic Acids Chemistry location:Kyoto, Japan date:8-12 September 2008
Abstract: A dideoxythymidine analog, viz. 3'-N, N-dimethyl-2'-3'-dideoxythymidine (3) and its 5'-O-carboxyl ester prodrug derivatives (4-6) have been synthesized as probable antiviral agents. All these compounds have shown low to moderate level of antiviral activities against HIV, HSV 1 & 2, reovirus and many others.
ISSN: 0261-3166
Publication status: published
KU Leuven publication type: IC
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
# (joint) last author

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