Title: Neoadjuvant Therapy Before Radical Prostatectomy: Impact on Progression Free Survival
Authors: Van Poppel, Hendrik ×
Goethuys, Hans
De Ridder, Dirk
Verleyen, Pieter
Ackaert, Koen
Werbrouck, Patrick
Decoster, Marina
Baert, Luc #
Issue Date: 2001
Publisher: Taylor & Francis Health Sciences
Series Title: UroOncology vol:1 pages:301-307
Abstract: In a multicenter randomized trial 160 patients were allocated to immediate radical prostatectomy or to preoperative neoadjuvant hormonal therapy followed by radical prostatectomy for clinical T2b and T3 prostate cancer. Comparing, prostate specific antigen (PSA)-free survival data and clinical relapse free survival, there was, at a mean follow-up of 43 months, no significant difference between the two treatment groups, not for the cT2 or cT3 subgroup, neither for the group as a whole. Although neoadjuvant hormonal therapy can significantly reduce the number of positive surgical margins, this approach does not decrease biochemical progression rates or does not improve clinical relapse free survival.
ISSN: 1561-0950
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Urology Section (-)
× corresponding author
# (joint) last author

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