ITEM METADATA RECORD
Title: Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines: a new class of pestivirus inhibitors
Authors: Puerstinger, G ×
Paeshuyse, Jan
Herdewijn, Piet
Rozenski, Jef
De Clercq, Erik
Neyts, Johan #
Issue Date: Oct-2006
Publisher: Pergamon Press
Series Title: Bioorganic & Medicinal Chemistry Letters vol:16 issue:20 pages:5345-5349
Abstract: A novel class of inhibitors of pestiviruses (5-substituted 2-phenyl-5H-imidazo[4,5-c]pyridines) is described. Modification of the substituent in position 5 resulted in analogues with high activity (EC(50)<100nM) and selectivity (SI>1000) against the pestivirus BVDV (bovine viral diarrhea virus).
ISSN: 0960-894X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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