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Title: Mouse models for peroxisome biogenesis disorders
Authors: Baes, Myriam # ×
Issue Date: Jan-2000
Series Title: Cell biochemistry and biophysics vol:32 Spring pages:229-37
Abstract: The gene knockout technology has been applied to generate mice lacking functional peroxisomes. These mice are a model for Zellweger syndrome and other peroxisome biogenesis disorders that are lethal in early life. Extensive biochemical, ultrastructural, and neurodevelopmental analyses indicate that the peroxisome deficient mice closely mimic the pathology in Zellweger patients and will be a very useful tool to elucidate the pathogenesis of this disease.
ISSN: 1085-9195
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Cell Metabolism
× corresponding author
# (joint) last author

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