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Title: Design, synthesis, and SAR of a novel pyrazinone series with non-nucleoside HIV-1 reverse transcriptase inhibitory activity
Authors: Heeres, Jan ×
de Jonge, Marc R
Koymans, Lucien M H
Daeyaert, Frits F D
Vinkers, Maarten
Van Aken, Koen J A
Arnold, Eddy
Das, Kalyan
Kilonda, Amuri
Hoornaert, Georges
Compernolle, Frans
Cegla, Marek
Azzam, Rasha A
Andries, Koen
de Béthune, Marie-Pierre
Azijn, Hilde
Pauwels, Rudi
Lewi, Paul J
Janssen, Paul A J #
Issue Date: Mar-2005
Series Title: Journal of Medicinal Chemistry vol:48 issue:6 pages:1910-8
Abstract: A series of novel pyrazinones designed as non-nucleoside reverse transcriptase inhibitors (NNRTIs) was synthesized and their anti-HIV structure-activity relationship (SAR) was studied.
URI: 
ISSN: 0022-2623
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Chemistry - miscellaneous
Molecular Design and Synthesis
× corresponding author
# (joint) last author

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