Title: The relationship between beta-blockade, hyporeninaemic and hypotensive effect of two beta-blocking agents
Authors: Amery, A ×
De Plaen, J F
Fagard, Robert
Linjen, P
Reybrouck, Tony #
Issue Date: Jan-1976
Series Title: Postgraduate medical journal vol:52 Suppl 4 pages:102-8
Abstract: In two consecutive series of hypertensive patients the hypotensive effect, the hyporeninaemic effect and the blockade of cardiac beta-receptors was studied using weekly increasing doses of propranolol or atenolol. With both beta-blockers, cardiac blockade and hypotensive effect increased in a parallel fashion when the dosage was increased suggesting that the hypotensive effect is related to cardiac beta-blockade. On the other hand lack of parallelism between the hypotensive effect and the hyporeninaemic effect suggests that the hypotensive effect was not related to a major extent to the hyporeninaemic effect of the drugs in the dosage range studied here.
ISSN: 0032-5473
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Hypertension and Cardiovascular Epidemiology
Research Group for Cardiovascular and Respiratory Rehabilitation
× corresponding author
# (joint) last author

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