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Title: Trisomy 7 and trisomy 8 in dividing and non-dividing tumor cells in Dupuytren's disease
Authors: Dal Cin, Paola ×
De Smet, Luc
Sciot, Raphael
Van Damme, Boudewijn
Van den Berghe, Herman #
Issue Date: Jan-1999
Publisher: Elsevier Science Pub. Co.
Series Title: Cancer Genetics and Cytogenetics vol:108 issue:2 pages:137-40
Abstract: Cytogenetic and molecular cytogenetic analysis is reported in a series of 40 tissue samples from 36 patients with Dupuytren's disease, presenting as palmar and/or finger nodules. No consistent structural chromosome changes could be found. Instead, recurrent clonal numerical abnormalities were demonstrated in 22 of 40 tissue nodules, involving trisomies of chromosome 7 or 8 and loss of the Y chromosome. In addition, we showed that trisomy 7 and trisomy 8 were also present in non-dividing cells.
ISSN: 0165-4608
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
Research Group for Musculoskeletal Rehabilitation
Clinical Genetics Section (-)
Department of Human Genetics - miscellaneous
× corresponding author
# (joint) last author

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