Title: Effects of 1-sar-8-ala-angiotensin II on arterial pressure, renin and aldosterone in hypertension
Authors: Fagard, Robert ×
Lijnen, Paul
Amery, A
Reybrouck, Tony #
Issue Date: Jan-1978
Series Title: Contributions to nephrology vol:11 pages:175-8
Abstract: 1-Sar-8-ala-angiotensin II did not change intra-arterial pressure in 25 sodium replete hypertensive patients, whilst the pressure changes were closely related to the plasma renin level during sodium depletion (r = -0.87; n = 32). The study indicates that arterial pressure is not dependent on angiotensin II in sodium replete patients and in sodium deplete subjects with low PRC, while it is angiotensin dependent during sodium depletion in the others. Plasma renin is unaffected in sodium replete subjects, but increases during saralasin in sodium deplete conditions. Saralasin stimulates aldosterone secretion only in sodium replete patients.
ISSN: 0302-5144
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Hypertension and Cardiovascular Epidemiology
Research Group for Cardiovascular and Respiratory Rehabilitation
× corresponding author
# (joint) last author

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