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Title: Cytogenetic characterization of tenosynovial giant cell tumors (nodular tenosynovitis)
Authors: Dal Cin, Paola ×
Sciot, Raphael
Samson, Ignace
De Smet, Luc
De Wever, Ivo
Van Damme, Boudewijn
Van den Berghe, Herman #
Issue Date: Aug-1994
Series Title: Cancer Research vol:54 issue:15 pages:3986-7
Abstract: Chromosome investigation in six localized forms of tenosynovial giant cell tumors, also known as modular tenosynovitis, revealed an identical translocation between chromosomes 1 and 2, t(1;2)(p11;q35-36) in three tumors, a variant translocation t(1;5)(p11;q22) in a fourth case, and a t(2;16)(q33;q24) in a fifth case. One case showed a normal karyotype. Although morphologically rather uniform, these benign tumors appear to be cytogenetically heterogeneous, but the chromosome changes seem to cluster in 2 regions, 1p11 and 16q24.
URI: 
ISSN: 0008-5472
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
Surgical Oncology
Research Group for Musculoskeletal Rehabilitation
Clinical Genetics Section (-)
Orthopaedics Section (-)
× corresponding author
# (joint) last author

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