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Title: Long-term creatine intake is beneficial to muscle performance during resistance training
Authors: Vandenberghe, K ×
Goris, Marina
Van Hecke, Paul
Van Leemputte, Marc
Vangerven, L
Hespel, Peter #
Issue Date: Dec-1997
Series Title: Journal of applied physiology (Bethesda, Md. : 1985) vol:83 issue:6 pages:2055-63
Abstract: The effects of oral creatine supplementation on muscle phosphocreatine (PCr) concentration, muscle strength, and body composition were investigated in young female volunteers (n = 19) during 10 wk of resistance training (3 h/wk). Compared with placebo, 4 days of high-dose creatine intake (20 g/day) increased (P < 0.05) muscle PCr concentration by 6%. Thereafter, this increase was maintained during 10 wk of training associated with low-dose creatine intake (5 g/day). Compared with placebo, maximal strength of the muscle groups trained, maximal intermittent exercise capacity of the arm flexors, and fat-free mass were increased 20-25, 10-25, and 60% more (P < 0. 05), respectively, during creatine supplementation. Muscle PCr and strength, intermittent exercise capacity, and fat-free mass subsequently remained at a higher level in the creatine group than in the placebo group during 10 wk of detraining while low-dose creatine was continued. Finally, on cessation of creatine intake, muscle PCr in the creatine group returned to normal within 4 wk. It is concluded that long-term creatine supplementation enhances the progress of muscle strength during resistance training in sedentary females.
ISSN: 8750-7587
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Radiology
Exercise Physiology Research Group
× corresponding author
# (joint) last author

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