Title: Oral creatine supplementation in humans does not elevate urinary excretion of the carcinogen N-nitrososarcosine
Authors: Derave, Wim ×
Vanden Eede, Els
Hespel, Peter
Carmella, Steven G
Hecht, Stephen S #
Issue Date: Mar-2006
Series Title: Nutrition (Burbank, Los Angeles County, Calif.) vol:22 issue:3 pages:332-3
Abstract: OBJECTIVE: Creatine is a popular oral supplement in athletes and may have therapeutical potential in neuromuscular diseases. It has been hypothesized that creatine ingestion can lead to increased formation of the carcinogen N-nitrososarcosine. METHODS: We investigated in a double-blind, placebo-controlled study the urinary excretion of N-nitrososarcosine after 1-wk high-dose (20 g/d) and 20-wk low-dose (5 g/d) creatine supplementation in healthy humans. RESULTS AND CONCLUSION: Creatine ingestion does not systematically increase urinary N-nitrososarcosine excretion.
ISSN: 0899-9007
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Exercise Physiology Research Group
× corresponding author
# (joint) last author

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