Title: Future directions in endometriosis research
Authors: D'Hooghe, Thomas ×
Kyama, Cleophas
Debrock, Sophie
Meuleman, Christel
Mwenda, Jason M #
Issue Date: Dec-2004
Publisher: New York Academy of Sciences
Series Title: Annals of the New York Academy of Sciences vol:1034 pages:316-325
Article number: Part VIII Endometriosis
Abstract: Endometriosis is an important gynecological disease, pathologically defined by the ectopic presence of both endometrial glands and stroma, and clinically associated with pelvic pain and infertility. Our current knowledge of the pathogenesis, pathophysiology of related infertility, and spontaneous evolution is still limited, although endometriosis has been described for many years. Future research in endometriosis needs to focus on pathogenesis studies in the baboon model and on the early interactions between endometrial and peritoneal cells in the pelvic cavity at the time of menstruation. Proteomic and genomic approaches are needed to detect potential differences between eutopic endometrium and myometrium in women with and without endometriosis. Immunomodulatory drugs inhibiting endometriosis-associated pelvic inflammation may offer new medical treatment for endometriosis in the future.
ISBN: 1-57331-536-2
ISSN: 0077-8923
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Reproductive Medicine Section (-)
Assisted Reproductive Technology Laboratory (-)
Section Woman - Miscellaneous (-)
Department of Development and Regeneration - miscellaneous (+)
× corresponding author
# (joint) last author

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