In the decades ahead, the number of families faced with caring for a person with Alzheimer’s Disease (AD) and related disorders will grow substantially. The number of estimated sufferers is estimated at between 0.9 and 1.2% of the total population. Formal and informal care, probably primarily the latter, will be mobilised to a significant extent. Some studies estimate the cost of care for AD patients at one-tenth to one-third of all care expenditure. However, the burden on the main carer will perhaps be even more difficult to support, primarily because it weighs almost exclusively on the (probably also elderly) partner or child of the AD sufferer. This paper presents images of the vulnerability of this care situation and the frailty of older persons with AD. With the financial support of the European Commission within the context of the EACH-project (European Alzheimer Clearing House) and co-financing from the Flemish Government, formal and informal care for persons with AD living at home was studied in detail in five European countries (Belgium (Flanders), Finland, Ireland, Greece and Spain). The Higher Institute for Labour Studies (HIVA) developed the methodology and co-ordinated the work of four other research institutes, each of them applying the research methodology in their own country on a limited or larger scale. This approach means that, for the first time, we have access to comparative information about the costs of formal and informal care. This volume contains the reports for the pilot studies in the five participating countries, as well as a comparative analysis.