Title: Cueing training in the home improves gait-related mobility in Parkinson's disease: The RESCUE-trial
Authors: Nieuwboer, Alice ×
Kwakkel, Gert
Rochester, Lynn
Jones, Diana
van Wegen, Erwin
Willems, Anne Marie
Chavret, Fabienne
Hetherington, Victoria
Baker, Katherine
Lim, Inge #
Issue Date: Feb-2007
Publisher: British Medical Association
Series Title: Journal of Neurology, Neurosurgery and Psychiatry vol:78 issue:2 pages:134-140
Abstract: OBJECTIVES: Gait and mobility problems remain difficult to treat in people with Parkinson's disease (PD). The RESCUE-trial investigated the effects of a home physiotherapy program based on rhythmical cueing on gait and gait-related activity. METHODS: A single-blind randomized cross-over trial was set up, including 153 patients with PD aged between 41 and 80 years and in Hoehn & Yahr stage II to IV. Subjects allocated to early intervention (N=76) received a three-week home cueing program using a prototype cueing device followed by three weeks without training. Patients allocated to late intervention (N=77) underwent the same intervention and control period in reverse order. After the initial 6 weeks, both groups had a six week follow-up without training. Posture and Gait scores (PG-scores) measured at 3, 6, and 12 weeks by blind testers were the primary outcome measure. Secondary outcomes included specific measures on gait, freezing and balance, functional activities, quality of life and carer strain. RESULTS: Small but significant improvements were found after intervention of 4.2% on the PG-scores (p=0.005). Severity of freezing was reduced by 5.5% as measured in freezers only (p=0.007). Gait speed (p=0.005), step length (p<.0001) and timed balance tests (p=0.003) improved in the full cohort. Other than a greater confidence to carry out functional activities (Falls Efficacy Scale, p=0.04), no carry-over effects were observed in functional and quality of life domains. Effects of intervention reduced significantly at 6 week follow-up. CONCLUSIONS: Cueing training in the home has specific effects on gait, freezing and balance. The wearing off of intervention effects underscores the need for permanent cueing devices and follow-up treatment. Cueing training may be a useful therapeutic adjunct to the overall management of gait disturbance in PD.
ISSN: 0022-3050
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Research Group for Neuromotor Rehabilitation
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science