Lecture Notes in Computer Science vol:4191 pages:718-725
9th International conference on medical image computing and computer assisted intervention - MICCAI 2006 location:Copenhagen, Denmark date:1-6 October 2006
We present a new approach for the registration of breast MR images, which are acquired at different time points for observation of lesion evolution. In this registration problem, it is of utmost importance to correct only for differences in patient positioning and to preserve other diagnostically important differences between both images, resulting from anatomical and pathological changes between both acquisitions. Classical free form deformation algorithms are therefore less suited, since they allow too large local volume changes and their deformation is not biomechanically based. Instead of adding constraints or penalties to these methods in order to restrict unwanted deformations, we developed a truly biomechanically based registration method where the position of skin and muscle surface are used as the only boundary conditions. Results of our registration method show an important improvement in correspondence between the reference and the deformed floating image, without introducing physically implausible deformations and within a short computational time.
Roose L., Mollemans W., Loeckx D., Maes F., Suetens P., ''Biomechanically based elastic breast registration using mass tensor simulation'', Lecture notes in computer science, vol. 4191, pp. 718-725, 2006 (Proceedings 9th international conference on medical image computing and computer assisted intervention - MICCAI 2006, October 1-6, 2006, Copenhagen, Denmark).