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[Poster Board #M55] Compliance with Activity Monitors in COPD, [Publication Page: A368] S. Battaglia, M.D., PhD., F. Sciurba, M.D., D. Langer, MSc., L. Martino, M.D., I. Weisman, M.D., D. Chapman, MSc., R.C. Hubbard, M.D., M. Decramer, M.D., Ph, T. Troosters, PhD., New York, NY, Pittsburgh, PA, Leuven, Belgium, Palermo, Italy Physical activities of daily life (PADL) have become a promising outcome for studies in COPD. Several methodological challenges need clarification before starting longitudinal multi-center studies. We studied: 1) patient compliance with wearing an activity monitor which estimates energy expenditure at different predetermined intensities, the number of steps and lying time (Sensewear Armband BodyMedia Pittsburgh, US: AB) 2) the day to day variability in PADL. 59 patients (Age 668 yrs, FEV1 5526% predicted) were recruited in three centers: Palermo, Italy, Leuven, Belgium and Pittsburgh, US. We analyzed the time patients wore the AB and the day-to-day variability and differences between week days and weekends. Compliance with wearing the device was excellent. On 83% of the days the compliance with 24h measurement was more than 90% of the time. The mean number of steps was 57253315.day-1, the time at a physical activity level of more than three METS (PA3) was 7963 min.day-1. The coefficients of variation for steps (3419%) and PA3 (6831%) were large. With 6 days of assessment the within subject SEM of the PADL was acceptable (749.day-1 for steps and 18min.day-1 for PA3), which indicates a more robust outcome. Compared to weekdays Sundays were consistently less active (-9822952 steps, p=0.001), PA3 (-2657min, p=0.001). We conclude that compliance with activity monitoring is excellent. Assessment of PA should last for up to six days, preferably excluding Sundays. Session Info: [**] Thematic Poster Session, [B38] EXERCISE IN COPD: FUNCTIONAL ASSESSSMENT Session Time: 8:15 AM - 4:15 PM Presentation Time: 8:15 AM Poster Viewing: 10:45 AM - 12:15 PM Room: Area M (Hall D, Lower Level), Moscone Center