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Title: Angiosarcoma of the larynx
Authors: Sciot, Raphael ×
Delaere, Pierre
Van Damme, B
Desmet, Valeer #
Issue Date: Jun-1995
Series Title: Histopathology vol:26 issue:2 pages:177-80
Abstract: The morphological and immunohistochemical features of a laryngeal angiosarcoma are described. Initially, the tumour was interpreted as a poorly differentiated squamous cell carcinoma. The laryngectomy specimen contained an extensive and haemorrhagic tumour consisting of irregular and dissecting vascular spaces delineated by pleomorphic endothelial cells. In addition to these obvious angiosarcomatous areas, islands of more compact growing tumour cells were present, reminiscent of a poorly differentiated squamous cell carcinoma. On immunohistochemistry, the tumour cells expressed factor VIII, Ulex europaeus I lectin, CD31 and vimentin. There was no expression of cytokeratin or epithelial membrane antigen. Angiosarcoma of the larynx is very rare and should be differentiated from a pseudo-angiosarcomatous carcinoma.
ISSN: 0309-0167
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
Research Group Experimental Oto-rhino-laryngology
Laboratory of Experimental Transplantation
× corresponding author
# (joint) last author

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