Tijdschrift voor geneeskunde

Publication date: 2006-01-01
Volume: 62 Pages: 368 - 374

Author:

Goegebuer, Alexander
Pirenne, Jacques ; Aerts, Raymond ; Nevens, Frederik

Abstract:

Liver transplantation is the lifesaving treatment of end-stage liver disease. There has been an increasing shortage of cadaveric grafts due to the increase of transplantation candidates. One alternative is adult-to-adult living donor liver transplantation. The most appropriate candidate-recipients are the patients with a good liver synthesis capacity, e.g. patients with cirrosis complicated with hepatocellular carcinoma. The actual short-term survival for living donor liver transplantation is similar to cadaveric liver transplantation. There occur, however, more biliary and vascular complications in the recipient. The primary concern remains the risk of morbidity of the healthy donor with a reported mortality risk of 0.5%.