Title: Langerhans cell histiocytosis of the cervical spine: a single institution experience in four patients
Authors: Tan, Grace ×
Samson, Ignace
De Wever, Ivo
Goffin, Jan
Demaerel, Philippe
Van Gool, Stefaan #
Issue Date: Apr-2004
Publisher: Raven Press
Series Title: Journal of Pediatric Orthopaedics. Part B vol:13 issue:2 pages:123-6
Abstract: When Langerhans cell histiocytosis (LCH) occurs at critical sites, such as in the cervical spine, there is a substantial risk for morbidity. Therefore, reports on clinical experiences with those patients remain important. We summarize the history of four patients with unifocal LCH at the cervical spine. All four patients received a biopsy to prove the histopathological diagnosis of LCH by demonstration of CD1a+cells. They were treated with oral prednisolone. All patients recovered completely and kept a normal function of the cervical spine. No reactivation of the disease occurred with an observation time of 3.4-7.3 years. This report contributes to the clinical experience for the treatment of LCH at critical sites.
ISSN: 1060-152X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Surgical Oncology
Research Group Experimental Neurosurgery and Neuroanatomy
Laboratory of Clinical Immunology
Laboratory of Pediatric Immunology
Translational MRI (+)
× corresponding author
# (joint) last author

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