Title: Measurement of the liver tissue oxygenation by near-infrared spectroscopy
Authors: Naulaers, Gunnar ×
Meyns, Bart
Miserez, Marc
Leunens, Veerle
Van Huffel, Sabine
Casaer, Paul
Devlieger, Hugo #
Issue Date: Jan-2005
Publisher: Springer International
Series Title: Intensive Care Medicine vol:31 issue:1 pages:138-141
Abstract: OBJECTIVE: To study the relation between the liver tissue oxygenation index (TOI), transcutaneously measured with spatially resolved spectroscopy (a new method of near-infrared spectroscopy or NIRS), the mixed venous oxygen saturation and the blood flow in the different parts of the splanchnic circulation in newborn piglets. DESIGN: Tissue oxygenation index of the liver was measured in six newborn piglets at 33 degrees C, 35 degrees C, 37 degrees C and after a decrease in arterial carbon dioxide pressure (PaCO(2)). MEASUREMENTS: Mixed venous oxygen saturation, blood gas analysis and peripheral oxygen saturation were measured at each step. Gastric, proximal jejunal, midgut, distal ileal, splenic and hepatic arterial blood flow were measured by injection of coloured microspheres into the left atrium. NIRS optodes were attached to the skin over the liver and TOI was calculated. RESULTS: No significant changes of TOI of the liver were seen during the increase in temperature or change in PaCO(2). TOI correlated well with mixed venous oxygen saturation (r=0.85), the mid-ileal blood flow (r=0.57) and the distal ileal blood flow (r=0.72). CONCLUSIONS: Measurement of the TOI of the liver might be a non-invasive way to measure the distal ileal blood flow.
ISSN: 0342-4642
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Section Newborn (-)
Abdominal Surgical Oncology
Clinical Cardiac Surgery
ESAT - STADIUS, Stadius Centre for Dynamical Systems, Signal Processing and Data Analytics
Section Child - Miscellaneous (-)
× corresponding author
# (joint) last author

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