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Title: Visual activation in prefrontal cortex is stronger in monkeys than in humans
Authors: Denys, Katrien ×
Vanduffel, Wim
Fize, Denis
Nelissen, Koen
Sawamura, Hiromasa
Georgieva, Svetlana
Vogels, Rufin
Van Essen, David
Orban, Guy #
Issue Date: Nov-2004
Publisher: MIT Press
Series Title: Journal of Cognitive Neuroscience vol:16 issue:9 pages:1505-1516
Abstract: The prefrontal cortex supports many cognitive abilities, which humans share to some degree with monkeys. The specialized functions of the prefrontal cortex depend both on the nature of its inputs from other brain regions and on distinctive aspects of local processing. We used functional MRI to compare prefrontal activity between monkey and human subjects when they viewed identical images of objects, either intact or scrambled. Visual object-related activation of the lateral prefrontal cortex was observed in both species, but was stronger in monkeys than in humans, both in magnitude (factors 2-3) and in spatial extent (fivefold or more as a percentage of prefrontal volume). This difference was observed for two different stimulus sets, at two field strengths, and over a range of tasks. These results suggest that there may be more volitional control over visual processing in humans than in monkeys.
ISSN: 0898-929X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Research Group Neurophysiology
Laboratory for Neuro- and Psychofysiology
× corresponding author
# (joint) last author

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