Title: Bromovinyldeoxyuridine and interferon treatment in ulcerative herpetic keratitis: a double masked study
Authors: van Bijsterveld, O P ×
Meurs, P J
De Clercq, Erik
Maudgal, P C #
Issue Date: Oct-1989
Series Title: British Journal of Ophthalmology vol:73 issue:8 pages:604-7
Abstract: Bromovinyldeoxyuridine is a potent and safe antiherpes compound that in combination with a placebo treatment promoted the partial and complete healing of herpetic epithelial disease in 22 patients in average times of 4-6 days and 8.5 days respectively. However, when BVDU was combined with 1.5 X 10(6) IU of recombinant a 2C interferon, partial and complete healing times for keratitis in 19 patients were reduced to 2-6 days and 4-6 days respectively. No toxic effects of the medications were observed in any patient.
ISSN: 0007-1161
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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