Title: Ontogeny of the sensitivity of the somatotrophs to thyrotropin releasing hormone (TRH) and growth hormone releasing factor (GRF) in the embryonic and posthatch chick
Authors: Darras, Veerle ×
Finné, Marie-France
Berghman, Luc
Kühn, Eduard #
Issue Date: 1994
Series Title: Annales d'Endocrinologie vol:55 issue:6 pages:255-260
Abstract: The ontogeny of the in vitro growth hormone (GH) release after stimulation with thyrotrophin releasing hormone (TRH) or growth hormone releasing factor (GRF) has been studied in two strains of chickens during the last week of embryonic development and the first week posthatch. Fourteen-day-old embryos did not yet respond to any of the stimuli applied, while the amplitude of the GH response to the different stimuli increased gradually from 18-day-old embryos to 1-day-old chicks. The evolution of the responses to both stimulating agents was parallel in the two strains of chickens, but the amplitude of the response was always higher in the rapidly growing broiler strain compared to the slowly growing layer strain. The highest GH response was at all stages obtained with the highest dose of GRF (100 nM). At a lower dose (10 nM), however, TRH seemed to be a more effective GH releasing agent than GRF at the posthatch stages.
ISSN: 0003-4266
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Animal Physiology and Neurobiology Section - miscellaneous
× corresponding author
# (joint) last author

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