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Title: Aggressive pituitary macroadenoma: CT and MR appearances
Authors: Van de Straete, S ×
Githeko, J
Demaerel, Philippe
Wilms, Guy
Lammens, M
Plets, Christiaan
Bouillon, Roger
Baert, A L #
Issue Date: 1996
Series Title: Journal Belge de Radiologie vol:79 issue:6 pages:255-7
Abstract: Two cases of aggressive pituitary macroadenoma (prolactinoma) with diffuse invasion of the skull base are described. Clinical signs usually appear late. CT shows the bone destruction, whereas MRI accurately delineates the extension of the tumor and involvement of the surrounding neurovascular structures. Histopathology and immunohistochemical staining are necessary for a definitive diagnosis differentiating prolactimonas from a wide range of skull base tumours and for deciding on additional therapy and prognosis. Aggressive pituitary macroadenoma is a large and diffuse tumor which is difficult to treat; therapy usually consists of extensive surgery, radiotherapy and pharmacotherapy with dopaminergic agents.
ISSN: 0021-7646
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Radiology
Research Group Experimental Neurosurgery and Neuroanatomy
Clinical and Experimental Endocrinology
Translational MRI (+)
× corresponding author
# (joint) last author

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