Title: Manofluorographic evaluation of swallowing in amyotrophic lateral sclerosis and its relationship with clinical evaluation of swallowing
Authors: Goeleven, Ann ×
Robberecht, Wim
Sonies, Barbara
Carbonez, An
Dejaeger, Eddy #
Issue Date: Dec-2006
Series Title: Amyotrophic Lateral Sclerosis vol:7 issue:4 pages:235-240
Abstract: The aim of this cross-sectional study was, first, to identify swallowing dysfunctions in an ALS population of 40 consecutive patients through combined videofluoroscopy and manometry. Secondly, these objective swallowing data were correlated with the functional feeding status as reported by the patient or family member. Videofluoroscopic evaluation showed dysfunctions in the oral phase of swallowing, pharyngeal initiation and pharyngeal transport. In addition, manometric data revealed low tongue driving forces and pharyngeal contraction amplitudes but normal relaxation of the upper oesophageal sphincter (UES). Aspiration was noted in a not negligible number of 9/40 patients. These objective data were then correlated with the clinical swallowing and feeding status, assessed by means of the ALS Swallowing Severity Scale. Patients receiving scores of 6 or lower on the ALSSSS, report dietary consistency changes but are considered 'safe oral feeders'. Nevertheless, our data revealed that these patients showed significant aspiration during videofluoroscopy. Although not every patient with ALS should be referred routinely for radiographic evaluation of swallowing, our findings suggest referral for a radiological examination as soon as the ALSSSS drops to a score of 6 or lower, to evaluate the presence of (silent) aspiration.
ISSN: 1748-2968
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Research Group Experimental Neurology
Gerontology and Geriatrics
Leuven Statistics Research Centre (LStat)
Research Group Experimental Oto-rhino-laryngology
Laboratory for Neurobiology
× corresponding author
# (joint) last author

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