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Title: A retrospective study of Creutzfeldt-Jakob disease in Belgium
Authors: Pals, P ×
Van Everbroeck, B
Sciot, Raphael
Godfraind, C
Robberecht, Wim
Dom, René
Laterre, C
Martin, J J
Cras, P #
Issue Date: Oct-1999
Series Title: European journal of epidemiology vol:15 issue:6 pages:517-9
Abstract: Using data from Belgian neuropathological archives, completed with the results of a comprehensive study of available medical records, we found 100 patients who fulfilled diagnostic criteria for probable or definite Creutzfeldt-Jakob d1551isease (CJD). Mean age at death was 63 years. The median disease duration was 9 months. Progressive mental deterioration was present in all cases, whereas signs of cerebellar dysfunction and myoclonus were found in approximately 80% of the patients. In 50% of the population, the EEG revealed characteristic abnormalities. Ninety-six patients suffered from the sporadic type of CJD, while 4 suffered from a hereditary form. In our series, we could find no evidence for the new variant, neither for an iatrogenic cause.
URI: 
ISSN: 0393-2990
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
Research Group Experimental Neurology
Laboratory for Neurobiology (Vesalius Research Center)
× corresponding author
# (joint) last author

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