Title: Use of a commercially available line probe assay for genotyping of hepatitis C virus 5a strains
Authors: Verbeeck, Jannick
Maes, Piet
Wollants, Elke
Van der Merwe, Schalk
Song, Ernie
Nevens, Frederik
Van Ranst, Marc # ×
Issue Date: Dec-2005
Series Title: Journal of clinical microbiology vol:43 issue:12 pages:6117-6119
Abstract: To validate a commercially available line probe assay for samples containing the infrequently found hepatitis C virus (HCV) genotype 5a, we sequenced a 511-nucleotide fragment of the NS4b region of Belgian and South African HCV genotype 5a samples. Phylogenetic analysis of the sequence data was performed. For the 77 HCV genotype 5a samples collected, there was 100% concordance between the genotype assignment by the line probe assay and the genotyping based on nucleotide sequencing, despite sequence heterogeneity in the probe binding sites of some samples.
ISSN: 0095-1137
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Clinical and Epidemiological Virology (Rega Institute)
× corresponding author
# (joint) last author

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