Tijdschrift voor geneeskunde vol:59 issue:1 pages:47-51
Rhabdomyolysis as a late complication of hyponatremia
Rhabdomyolysis is a complication which may occur during or after the correction of hyponatremia.
This case report describes a 47-year old female treated with paroxetine for two days. Then she developed a SIADH with hyponatremia followed by rhabdomyolysis.
This case demonstrates that hyponatremia and hypo-osmolality can cause a potassium depletion in muscle cells, which in turn can cause a rhabdomyolysis. Therefore it is important for clinicians to monitor conscientiously muscle enzymes in patients with severe hyponatremia, and especially when they exhibit myalgia.