Title: Is the predictive power of a low-pulse pressure independent of peak oxygen uptake in advanced chronic heart failure?
Authors: Fagard, Robert ×
Pardaens, Karel
Vanhaecke, Johan #
Issue Date: Jan-2008
Publisher: Nature publishing group
Series Title: Journal of human hypertension vol:22 issue:1 pages:57-59
Abstract: A pulse pressure (PP) below 35-40mm Hg has been shown to carry a worse prognosis in patients with chronic heart failure (CHF), but its non-dependence on peak oxygen uptake, which is a major if not the major prognostic factor in these patients, has not been studied. We assessed whether PP adds prognostic precision to peak oxygen uptake in 284 patients with advanced CHF, in whom blood pressure (BP) was measured at rest and who performed a graded symptom-limited bicycle exercise test with respiratory gas analysis. The results confirm that a low PP rather than a high PP predicts cardiovascular (CV) mortality in patients with CHF and that PP adds prognostic value to peak oxygen uptake, which is the strongest predictor of outcome.
ISSN: 0950-9240
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Cardiology
Hypertension and Cardiovascular Epidemiology
Research Group for Cardiovascular and Respiratory Rehabilitation
× corresponding author
# (joint) last author

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