Title: Stereoselective synthesis of (-)-ara-cyclohexenyl-adenine
Authors: Horváth, András
Ruttens, Bart
Herdewijn, Piet # ×
Issue Date: 2007
Publisher: Pergamon Press
Series Title: Tetrahedron vol:48 pages:3621-3623
Abstract: A stereoselective synthesis leading to (-)-ara-cyclohexenyl-adenine is described. The synthesis starts from methyl-alpha-D-glucopyranose and involves an isomerization step, selective protection/deprotection chemistry, a Ferrier rearrangement and a Mitsunobu reaction. This is the first total synthesis of an enantiomeric pure ara-type cyclohexenyl nucleoside.
ISSN: 0040-4020
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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