Title: Preparation of Guanine and Diaminopurine from Biuret
Authors: Lagoja, Irene ×
Herdewijn, Piet #
Issue Date: 2007
Publisher: Verlag Helvetica Chimica Acta
Series Title: Chemistry & Biodiversity vol:4 issue:4 pages:818-822
Abstract: Because of their potential prebiotic origin and relative chemical stability, urea, biuret, formic acid,
and glycine amide might have played a role in the assembly process of purine bases. In this paper, we describe a short reaction path to purine nucleobases from these acyclic precursors. The formation of different purines was verified by UV and NMR spectroscopy, as well as by mass spectrometry.
ISSN: 1612-1872
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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